Description

(S)-3-(Dimethylamino)-1,2-Propanediol CAS NO 666234-82-8 is a high-purity chiral amino alcohol building block of significant importance in asymmetric synthesis. Its value lies in its role as a versatile intermediate for constructing complex pharmaceutical molecules and fine chemicals. This product is essential for research and development chemists, process chemists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require enantiomerically pure intermediates for the production of active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) drugs and β-blockers.
• Asymmetric Catalyst Ligand Precursor: Used to derive chiral ligands for metal-catalyzed asymmetric reactions, including hydrogenation and carbon-carbon bond formation.
• Agrochemical Synthesis: Serves as a building block for creating chiral herbicides, fungicides, and plant growth regulators with enhanced efficacy and selectivity.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances where optical purity is critical.
• Academic & Industrial R&D: A valuable reagent for method development and exploring new synthetic pathways in organic and medicinal chemistry laboratories.

Basic Information

Product Name	(S)-3-(Dimethylamino)-1,2-Propanediol
CAS No.	666234-82-8
Molecular Formula	C5H13NO2
Molecular Weight	119.16 g/mol
Synonyms	(S)-3-(Dimethylamino)propane-1,2-diol; (S)-1,2-Propanediol, 3-(dimethylamino)-; (S)-DMAPD; (S)-3-Dimethylaminopropane-1,2-diol; (2S)-3-(Dimethylamino)-1,2-propanediol; (S)-3-(N,N-Dimethylamino)-1,2-propanediol; (S)-3-(Dimethylamino)-1,2-dihydroxypropane; (S)-Amino Diol Derivative
EINECS	Contact for details

Quality Control

Our (S)-3-(Dimethylamino)-1,2-Propanediol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high chemical and enantiomeric purity, meeting the stringent requirements for pharmaceutical R&D and production. A detailed Certificate of Analysis (COA) providing specifications for identity, purity, and chiral excess is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.