Description

7-Aza-n-Indolyldiphenylphosphine is a specialized organophosphorus ligand featuring a unique heterocyclic framework. This compound is valued for its ability to modulate the reactivity and selectivity of transition metal catalysts in complex synthetic transformations. It is primarily utilized by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and advanced intermediates.

Application

• As a ligand in cross-coupling reactions, such as Suzuki-Miyaura and Buchwald-Hartwig amination, for C-C and C-N bond formation.
• In asymmetric catalysis for the synthesis of enantiomerically pure pharmaceutical intermediates.
• For the development of novel metal-organic complexes with tailored electronic and steric properties.
• As a key reagent in academic and industrial R&D for exploring new catalytic methodologies.
• In the synthesis of complex heterocyclic compounds and natural product analogs.
• For process optimization and scale-up in fine chemical and active pharmaceutical ingredient (API) manufacturing.

Basic Information

Product Name	7-Aza-n-Indolyldiphenylphosphine
CAS No.	663219-75-8
Molecular Formula	C24H19N2P
Molecular Weight	366.40 g/mol
Synonyms	7-Azaindolyldiphenylphosphine; 7-Aza-1H-indol-1-yl-diphenylphosphine; Diphenyl(7-azaindol-1-yl)phosphine; 1-(Diphenylphosphino)-7-azaindole; 1H-Pyrrolo[2,3-b]pyridin-1-yldiphenylphosphine
EINECS	Contact for details

Quality Control

Our 7-Aza-n-Indolyldiphenylphosphine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical characterization, including NMR, HPLC, and elemental analysis, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its sensitivity, the container should be kept tightly sealed when not in use to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.