Description

Methyl 3-Fluoro-5-(Hydroxymethyl)Benzoate is a high-purity fluorinated benzoate derivative that serves as a versatile and critical building block in advanced organic synthesis. Its unique structure, featuring both a reactive hydroxymethyl group and a fluorine atom, makes it an invaluable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drug candidates targeting central nervous system (CNS) disorders, oncology, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom can enhance biological activity, stability, and selectivity.
• Liquid Crystal & OLED Materials: Serves as a precursor in the development of fluorinated components for electronic display materials and organic light-emitting diodes (OLEDs), improving performance and durability.
• Polymer Modification: Employed to introduce fluorinated benzoate groups into polymer chains, modifying thermal stability, chemical resistance, and surface properties of specialty plastics and coatings.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new fluorination chemistry, cross-coupling reactions, and as a scaffold for library synthesis in drug discovery.

Basic Information

Product Name	Methyl 3-Fluoro-5-(Hydroxymethyl)Benzoate
CAS No.	660416-37-5
Molecular Formula	C9H9FO3
Molecular Weight	184.16 g/mol
Synonyms	3-Fluoro-5-(hydroxymethyl)benzoic acid methyl ester; Methyl 3-fluoro-5-(hydroxymethyl)benzoate; Benzoic acid, 3-fluoro-5-(hydroxymethyl)-, methyl ester; 5-(Hydroxymethyl)-3-fluorobenzoic acid methyl ester; Methyl 5-(hydroxymethyl)-3-fluorobenzoate
EINECS	Contact for details

Quality Control

Our production of Methyl 3-Fluoro-5-(Hydroxymethyl)Benzoate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for sensitive synthetic applications. Each lot is analyzed using advanced techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.