Description

2-Oxetanone,3-Ethyl-4-[(Phenylmethoxy)Methyl]-,(3R,4R)-(9Ci) CAS NO 652150-92-0 is a high-purity, stereochemically defined chiral building block belonging to the oxetanone class. This compound is of significant value in advanced organic synthesis, particularly for constructing complex molecular architectures with precise three-dimensional control. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), especially in oncology, antiviral, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the synthesis of advanced, stereoselective pesticides and herbicides where specific chirality can enhance efficacy and reduce environmental impact.
• Advanced Material Precursor: Serves as a building block for specialty polymers and liquid crystals that require specific optical or mechanical properties derived from its rigid oxetane ring structure.
• Asymmetric Catalysis Research: Employed as a substrate or ligand precursor in academic and industrial research focused on developing new asymmetric synthetic methodologies.
• Peptidomimetics & Bioisosteres: The oxetane ring is a valuable bioisostere for carbonyl or gem-dimethyl groups, making this compound useful in designing peptide mimics and improving drug metabolic stability.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis organizations (CSOs) and CDMOs producing bespoke compounds for client projects under cGMP or research-grade conditions.

Basic Information

Product Name	2-Oxetanone,3-Ethyl-4-[(Phenylmethoxy)Methyl]-,(3R,4R)-(9Ci)
CAS No.	652150-92-0
Molecular Formula	C13H16O3
Molecular Weight	220.26 g/mol
Synonyms	(3R,4R)-3-Ethyl-4-[(benzyloxy)methyl]oxetan-2-one; (3R,4R)-3-Ethyl-4-(phenylmethoxymethyl)-2-oxetanone; 3-Ethyl-4-[(phenylmethoxy)methyl]oxetan-2-one, (3R,4R)-; (3R,4R)-3-Ethyl-4-(benzyloxymethyl)oxetan-2-one; 652150-92-0; BBL 36007; A chiral β-lactone derivative; 4-(Benzyloxymethyl)-3-ethyloxetan-2-one, (3R,4R)-
EINECS	Contact for details

Quality Control

Every batch of (3R,4R)-3-Ethyl-4-[(benzyloxy)methyl]oxetan-2-one is manufactured and analyzed under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and stereochemical integrity, which are critical for sensitive chiral synthesis. Certificates of Analysis (COA) detailing specifications such as chiral purity (enantiomeric excess), chemical purity (HPLC), and identity confirmation (NMR, IR) are available for each lot. Our quality commitment supports applications from research to development under cGMP guidelines where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.