Description

3-(4-Methylimidazol-1-Yl)-5-Trifluoromethylbenzoic Acid is a high-value, multifunctional heterocyclic carboxylic acid building block. Its molecular structure, featuring both an imidazole ring and a trifluoromethyl group, makes it a critical intermediate for synthesizing advanced materials and active pharmaceutical ingredients (APIs). This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel compounds with enhanced biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and anti-inflammatory research.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, leveraging the bioactivity of the imidazole moiety.
• Ligand & Catalyst Precursor: Serves as a building block for N-heterocyclic carbene (NHC) ligands and other organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functional polymers and organic electronic materials due to its conjugated system and fluorine content.
• Chemical Biology Probe Development: Utilized to create molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom chemical synthesis services targeting niche applications.

Basic Information

Product Name	3-(4-Methylimidazol-1-Yl)-5-Trifluoromethylbenzoic Acid
CAS No.	641571-13-3
Molecular Formula	C12H9F3N2O2
Molecular Weight	270.21 g/mol
Synonyms	5-(Trifluoromethyl)-3-(4-methyl-1H-imidazol-1-yl)benzoic Acid; 3-(4-Methyl-1-imidazolyl)-5-(trifluoromethyl)benzoic Acid; Benzoic acid, 3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)-; 641571-13-3; 3-(4-Methylimidazol-1-yl)-5-trifluoromethylbenzoic acid
EINECS	Contact for details

Quality Control

Our production of 3-(4-Methylimidazol-1-Yl)-5-Trifluoromethylbenzoic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.