Description

5-Amino-2,4-Difluorobenzoic Acid, 98% is a high-purity fluorinated benzoic acid derivative serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of amino and fluorine substituents, which are essential for modulating the electronic properties, lipophilicity, and metabolic stability of target molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the difluoro and amino groups contribute to biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis, enabling novel synthetic transformations.
• Material Science Research: Employed in the synthesis of functionalized monomers for specialty polymers, liquid crystals, and organic electronic materials.
• Fluorine Chemistry Research: An important substrate for studying regioselective reactions and further functionalization of polyfluorinated aromatic systems.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in client-specific, multi-step synthetic routes.

Basic Information

Product Name	5-Amino-2,4-Difluorobenzoic Acid, 98%
CAS No.	639858-45-0
Molecular Formula	C7H5F2NO2
Molecular Weight	173.12 g/mol
Synonyms	2,4-Difluoro-5-aminobenzoic Acid; 5-Amino-2,4-difluorobenzoic Acid; Benzoic acid, 5-amino-2,4-difluoro-; 2,4-Difluoro-5-aminobenzoic acid; 5-Amino-2,4-difluoro-benzoic acid; 639858-45-0; 5-Amino-2,4-difluorobenzoic acid
EINECS	Contact for details

Quality Control

Our 5-Amino-2,4-Difluorobenzoic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity verification and identity confirmation by FT-IR and NMR, to ensure it meets the specified 98% purity grade. A detailed Certificate of Analysis (COA) documenting all test results is provided with each shipment and is available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed when not in use to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.