Description

Esreboxetine Succinate is a high-purity active pharmaceutical ingredient (API) and a selective norepinephrine reuptake inhibitor (NRI). This compound is critical for pharmaceutical research and development, offering a well-defined chemical entity for neurological and psychiatric studies. It is primarily utilized by pharmaceutical manufacturers, contract research organizations (CROs), and academic institutions engaged in the development of novel therapeutic agents.

Application

• Pharmaceutical API: Serves as the active ingredient in the formulation of prescription medications.
• Neurological Research: Used in preclinical and clinical research targeting depression and related mood disorders.
• Reference Standard: Acts as a certified reference material (CRM) for analytical method development and quality control in laboratories.
• Mechanistic Studies: Employed in pharmacological studies to investigate norepinephrine reuptake inhibition mechanisms.
• Drug Development Intermediates: Utilized in the synthesis of more complex drug candidates or prodrugs.
• Academic & Institutional Research: Supports basic science and translational research in universities and government institutes.

Basic Information

Product Name	Esreboxetine Succinate
CAS No.	635724-55-9
Molecular Formula	C19H25NO6
Molecular Weight	363.41 g/mol
Synonyms	Esreboxetine Succinate; (S,S)-Reboxetine Succinate; (2S,3S)-2-[(2-Ethoxyphenoxy)phenylmethyl]morpholine Succinate; PNU-165442G; PNU-165442; PNU 165442G; PNU 165442
EINECS	Contact for details

Quality Control

Our Esreboxetine Succinate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical-grade materials. Certificates of Analysis (COA) detailing specifications such as assay, related substances, and residual solvents are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.