Description

Asunaprevir CAS NO 630420-16-5 is a potent and selective inhibitor of the hepatitis C virus (HCV) NS3/4A protease. This compound is a critical active pharmaceutical ingredient (API) in the development of direct-acting antiviral (DAA) therapies for chronic HCV infection. It is primarily required by pharmaceutical manufacturers, research institutions, and contract development and manufacturing organizations (CDMOs) engaged in antiviral drug development and production.

Application

• Active Pharmaceutical Ingredient (API) for the formulation of direct-acting antiviral (DAA) combination therapies.
• Pharmaceutical Research & Development for studying HCV protease inhibition mechanisms and resistance profiles.
• Reference Standard in analytical laboratories for quality control and method development of antiviral drugs.
• Preclinical and Clinical Studies as a key component in investigational new drug (IND) applications.
• Contract Manufacturing for the production of finished dosage forms under cGMP conditions.
• Academic Research in virology and medicinal chemistry for novel antiviral discovery programs.

Basic Information

Product Name	Asunaprevir
CAS No.	630420-16-5
Molecular Formula	C35H46N4O7S
Molecular Weight	666.83 g/mol
Synonyms	BMS-650032; Asunaprevir sodium; BMS 650032; (1R,2S,5S)-N-[(1S)-1-[(2S)-2-[[(1S,2R)-1-[(Cyclopropylsulfonyl)carbamoyl]-2-ethenylcyclopropyl]amino]-3,3-dimethyl-1-oxobutyl]-2,2-dimethylpropyl]-3-[(2S)-2-[[(7-methoxy-2-phenylquinolin-4-yl)oxy]methyl]morpholin-4-yl]-3-oxopropane-1-sulfonamide; BMS650032; Asunaprevir (BMS-650032); UNII-6KZ25R5I02
EINECS	Contact for details

Quality Control

Our Asunaprevir is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets stringent specifications for pharmaceutical use, including identity, purity, and impurity profiles. Certificates of Analysis (COA) are provided, detailing results from tests such as HPLC assay, chiral purity, residual solvents, and heavy metals, in compliance with ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥98.5%
Related Substances (HPLC)	Total impurities ≤1.5% Any single unknown impurity ≤0.5%
Chiral Purity (HPLC)	≥99.5%
Residual Solvents (GC)	Complies with ICH Q3C
Heavy Metals	≤20 ppm
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.