Description

Pradefovir is a potent nucleotide analog prodrug designed for targeted therapeutic action. This compound is of significant interest in advanced pharmaceutical research and development due to its specific mechanism of action. It is primarily utilized by research institutions and pharmaceutical companies engaged in antiviral drug discovery and development programs.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of advanced antiviral active pharmaceutical ingredients (APIs).
• Antiviral Research: Used as a reference standard and active compound in preclinical studies targeting viral infections.
• Biochemical Research: Employed in enzymatic and cellular assays to study nucleotide metabolism and drug activation pathways.
• Drug Discovery: A key candidate in medicinal chemistry programs aimed at developing novel prodrug therapies with enhanced efficacy and reduced side effects.
• Analytical Standard: Provides a high-purity benchmark for quality control and method development in analytical laboratories (HPLC, LC-MS).

Basic Information

Product Name	Pradefovir
CAS No.	625095-61-6
Molecular Formula	C20H28N5O8P
Molecular Weight	497.44 g/mol
Synonyms	PMEA Prodrug; 9-[2-[[(S)-[[(1S)-1-(Isopropoxycarbonyl)ethoxy]phenoxyphosphinyl]methoxy]ethyl]adenine; (S)-HPMPA diphosphate prodrug; GS-7340 (developmental code); Pradefovirum; PMEA bis(POM)
EINECS	Contact for details

Quality Control

Our Pradefovir is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS). A Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to ensure compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.