Description

1,2-Ethanediol, 1-(4-Hydroxyphenyl)-, (1S)- (9Ci) is a chiral, hydroxyl-functionalized ethanediol derivative, serving as a valuable synthetic intermediate and building block in advanced organic chemistry. Its precise stereochemistry and bifunctional nature make it critical for constructing complex molecules with defined spatial orientation. This compound is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and specialty chemical sectors for developing active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in enantioselective drug development.
• Agrochemical Research: Used in the creation of novel, stereospecific herbicides, fungicides, and plant growth regulators.
• Liquid Crystal & Polymer Chemistry: Serves as a monomer or precursor for synthesizing advanced polymers and liquid crystal materials with specific optical properties.
• Asymmetric Catalyst Ligand Synthesis: A precursor for developing chiral ligands used in homogeneous catalysis for fine chemical production.
• Bioconjugation & Linker Chemistry: Its hydroxyl and phenyl groups facilitate its use in creating cleavable linkers for bioconjugation applications in diagnostics and drug delivery systems.
• Academic & Industrial R&D: A high-purity reagent for methodological development in synthetic organic chemistry and material science research.

Basic Information

Product Name	1,2-Ethanediol, 1-(4-Hydroxyphenyl)-, (1S)- (9Ci)
CAS No.	622854-00-6
Molecular Formula	C8H10O3
Molecular Weight	154.16 g/mol
Synonyms	(S)-1-(4-Hydroxyphenyl)ethane-1,2-diol; (1S)-1-(4-Hydroxyphenyl)-1,2-ethanediol; (S)-1,2-Dihydroxy-1-(4-hydroxyphenyl)ethane; L-1-(4-Hydroxyphenyl)glycol; (S)-p-Hydroxyphenylglycol; (S)-HPG; A chiral derivative of phenylethylene glycol; (S)-1-(4'-Hydroxyphenyl)-1,2-ethanediol
EINECS	Contact for details

Quality Control

Our production of 1,2-Ethanediol, 1-(4-Hydroxyphenyl)-, (1S)- (9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot undergoes comprehensive analytical characterization, including chiral purity verification by HPLC and structural confirmation by NMR and IR spectroscopy. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which may affect stability and purity. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.