Description

Nicotinehydrochloride is the hydrochloride salt form of nicotine, a naturally occurring alkaloid. This high-purity salt form offers enhanced stability and solubility, making it a critical intermediate for advanced pharmaceutical and research applications. It is primarily utilized by manufacturers in the pharmaceutical, agrochemical, and life science research sectors for the synthesis of active pharmaceutical ingredients (APIs), reference standards, and other specialized compounds.

Application

• Pharmaceutical Intermediate: Key starting material or intermediate in the synthesis of nicotine-based therapeutics, smoking cessation aids, and other active pharmaceutical ingredients (APIs).
• Analytical Reference Standard: Used as a certified reference material (CRM) in quality control laboratories for HPLC, GC, and other analytical methods to quantify nicotine content.
• Agrochemical Research: Employed in the research and development of novel insecticides and pesticides that target the nicotinic acetylcholine receptor (nAChR) in pests.
• Biochemical Research: Essential reagent in neuroscience and pharmacological studies investigating the cholinergic system, receptor binding, and signal transduction pathways.
• Veterinary Medicine: Component in the formulation of certain veterinary pharmaceuticals used for parasite control.

Basic Information

Product Name	Nicotinehydrochloride
CAS No.	69782-38-3
Molecular Formula	C10H15ClN2
Molecular Weight	198.69 g/mol
Synonyms	Nicotine Hydrochloride; (-)-Nicotine Hydrochloride; (S)-Nicotine Hydrochloride; 3-[(2S)-1-Methylpyrrolidin-2-yl]pyridine hydrochloride; Nicotine HCl; Nicotine Monohydrochloride; L-Nicotine Hydrochloride; Pyridine, 3-[(2S)-1-methyl-2-pyrrolidinyl]-, hydrochloride (1:1)
EINECS	Contact for details

Quality Control

Our Nicotinehydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, assay, and impurity profiling, to ensure it meets stringent specifications for pharmaceutical and research use. Certificates of Analysis (COA) detailing purity, residual solvents, and heavy metals are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤20 ppm
Specific Rotation	-80° to -90° (c=2 in H2O)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.