Description

(R)-(-)-n-(3,5-Dinitrobenzoyl)-α-Phenylethylamine CAS NO 69632-32-2 is a high-purity chiral derivatizing agent and analytical standard of significant importance in stereochemical analysis. Its core value lies in its ability to resolve enantiomers of chiral amines and alcohols via diastereomeric salt formation or HPLC analysis, enabling precise determination of optical purity. This compound is essential for research and quality control laboratories in the pharmaceutical, agrochemical, and fine chemical industries where chiral specificity is critical.

Application

• Chiral Resolution Agent: Used for the preparative separation of racemic mixtures of amines and amino acids via diastereomeric crystallization.
• Analytical Derivatization: Serves as a chiral derivatizing agent for HPLC and LC-MS analysis to determine enantiomeric excess (ee) of chiral compounds.
• Pharmaceutical Intermediate: Acts as a key chiral auxiliary or building block in the asymmetric synthesis of active pharmaceutical ingredients (APIs).
• Reference Standard: Employed as a certified reference material (CRM) for method development and validation in analytical chemistry.
• Academic & Industrial Research: Utilized in studies of stereoselective reactions, catalysis, and the development of new chiral separation methodologies.
• Quality Control: Critical for ensuring the enantiomeric purity of chiral drugs and fine chemicals in compliance with regulatory standards.

Basic Information

Product Name	(R)-(-)-n-(3,5-Dinitrobenzoyl)-α-Phenylethylamine
CAS No.	69632-32-2
Molecular Formula	C15H13N3O5
Molecular Weight	315.28 g/mol
Synonyms	(R)-(-)-N-(3,5-Dinitrobenzoyl)-α-phenylethylamine; (R)-N-(3,5-Dinitrobenzoyl)-1-phenylethylamine; (R)-DNB-PEA; (R)-(-)-1-Phenylethylamine-3,5-dinitrobenzamide; (R)-α-Methylbenzylamine-3,5-dinitrobenzamide; DNB-(R)-PEA; (R)-DNBPEA; (R)-1-(3,5-Dinitrobenzamido)ethylbenzene
EINECS	Contact for details

Quality Control

Our (R)-(-)-n-(3,5-Dinitrobenzoyl)-α-Phenylethylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric purity, NMR, and IR for structural confirmation, to ensure compliance with high-purity standards for research and analytical applications. Certificates of Analysis (COA) detailing purity, physical properties, and chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.