Description

Acetyl Coenzyme A, [Acetyl-1,2-14C] is a radiolabeled biochemical reagent essential for tracing metabolic pathways. This compound is critical for researchers requiring precise quantification and tracking of acetyl group transfer in enzymatic reactions. It is primarily used by scientists in pharmaceutical R&D, metabolic studies, and biochemical research to investigate key processes like the citric acid cycle and fatty acid synthesis.

Application

• Metabolic Pathway Tracing: Used as a radiolabeled tracer to study the citric acid cycle (Krebs cycle), fatty acid synthesis, and cholesterol biosynthesis.
• Enzyme Kinetics & Mechanism Studies: Essential for assays measuring the activity of acetyltransferases, including histone acetyltransferases (HATs) and choline acetyltransferase.
• Pharmaceutical Research: Employed in drug discovery to investigate the mechanism of action of compounds targeting metabolic enzymes and pathways.
• Biochemical Research: Serves as a substrate for in vitro studies of acetylation reactions and energy metabolism.
• Diagnostic Development: Can be utilized in the development of clinical assays for metabolic disorders.

Basic Information

Product Name	Acetyl Coenzyme A, [Acetyl-1,2-14C]
CAS No.	69321-00-2
Molecular Formula	C23H38N7O17P3S (with 14C label on acetyl group)
Molecular Weight	~809.57 g/mol (unlabeled)
Synonyms	Acetyl-CoA, [1,2-14C]Acetyl-Coenzyme A; Acetyl CoA-1,2-14C; Coenzyme A, S-acetate-1,2-14C; Acetyl-Coenzyme A, labeled; S-Acetylcoenzyme A-1,2-14C; 14C-Acetyl-CoA; Acetyl-CoA (14C-labeled)
EINECS	Contact for details

Quality Control

Every batch of Acetyl Coenzyme A, [Acetyl-1,2-14C] is manufactured and tested to meet stringent quality standards for radiochemical purity and specific activity. Our quality assurance includes rigorous analysis via HPLC and radio-HPLC to ensure product integrity and performance. Certificates of Analysis (COA) detailing specific activity, radiochemical purity, and analytical methods are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store frozen at or below -20°C. This product is hygroscopic (moisture-sensitive). Allow the vial to reach ambient temperature before opening to minimize moisture absorption. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white powder or lyophilized solid
Specific Activity	50-60 mCi/mmol (Contact for exact value)
Radiochemical Purity (HPLC)	≥ 95%
Chemical Purity (HPLC)	≥ 90%
Solvent	Lyophilized or specified aqueous buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.