Description

Brivudine is a synthetic nucleoside analogue with potent antiviral activity, primarily against herpesviruses. Its value lies in its targeted mechanism of action, which inhibits viral DNA replication with high selectivity, making it a crucial active pharmaceutical ingredient (API) for antiviral formulations. This compound is essential for pharmaceutical manufacturers and research institutions developing treatments for conditions like herpes zoster (shingles).

Application

• Pharmaceutical API: Primary use as the active ingredient in antiviral medications.
• Antiviral Research: A key reference standard and investigational compound in virology and drug discovery.
• Dosage Form Development: Used in the formulation of tablets, creams, and other topical or oral antiviral products.
• Biochemical Studies: Employed to study viral enzyme inhibition and nucleoside metabolism pathways.

Basic Information

Product Name	Brivudine
CAS No.	69304-47-8
Molecular Formula	C11H13BrN2O5
Molecular Weight	333.14 g/mol
Synonyms	(E)-5-(2-Bromovinyl)-2'-deoxyuridine; BVDU; Bromovinyldeoxyuridine; Brivudin; Helpin; Zostex; 1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-[(E)-2-bromoethenyl]pyrimidine-2,4(1H,3H)-dione
EINECS	Contact for details

Quality Control

Our Brivudine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with specifications for identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Individual Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Microbial Enumeration	Complies with Ph. Eur. 2.6.12/2.6.13

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.