Description

o-(α-L-Idopyranosyluronic Acid 2-Sulfate-(1-4)-2,5-Anhydro-Mannitol-6-Sulfate is a chemically defined, sulfated disaccharide derivative of significant interest in advanced biochemical research and development. This compound serves as a critical reference standard and building block for investigating carbohydrate-protein interactions, particularly those involving heparin-binding domains. Its precise structure makes it invaluable for pharmaceutical companies and research institutions focused on anticoagulant mechanisms, glycobiology, and the development of novel carbohydrate-based therapeutics.

Application

• Pharmaceutical Reference Standard: Used as a high-purity calibrant and control material in the analysis and quality control of heparin-related products and low-molecular-weight heparins (LMWHs).
• Biochemical Research: Serves as a key substrate or inhibitor in enzymatic studies to understand the specificity of sulfatases, glycosidases, and heparinases.
• Drug Discovery: Acts as a precise structural motif for designing and screening new anticoagulant, anti-inflammatory, or antiviral agents that target sulfated carbohydrate-mediated pathways.
• Glycobiology Studies: Essential for probing the structure-activity relationships of heparan sulfate proteoglycans and their role in cell signaling, growth factor binding, and disease progression.
• Diagnostic Development: Utilized in the development of diagnostic assays and kits that detect or quantify specific enzymatic activities or carbohydrate biomarkers.

Basic Information

Product Name	o-(α-L-Idopyranosyluronic Acid 2-Sulfate-(1-4)-2,5-Anhydro-Mannitol-6-Sulfate
CAS No.	69180-27-4
Molecular Formula	C12H16O18S2
Molecular Weight	488.37 g/mol
Synonyms	2-O-Sulfo-α-L-idopyranosyluronic acid-(1→4)-2,5-anhydro-6-O-sulfo-D-mannitol; Iduronic acid 2-sulfate-anhydromannitol 6-sulfate; Heparin disaccharide derivative δUA2S-AnMan6S; 2-Sulfo-α-L-iduronic acid-1,4-6-sulfo-2,5-anhydro-D-mannitol; HS Disaccharide 2S-6S; 2-O-Sulfo-α-L-idopyranosyluronic acid 1→4 linked to 2,5-anhydro-6-O-sulfo-D-mannitol; 69180-27-4
EINECS	Contact for details

Quality Control

Every batch of o-(α-L-Idopyranosyluronic Acid 2-Sulfate-(1-4)-2,5-Anhydro-Mannitol-6-Sulfate is manufactured under controlled conditions and undergoes rigorous analytical characterization to ensure structural integrity and purity. We provide comprehensive Certificates of Analysis (COA) detailing results from NMR (1H, 13C), mass spectrometry, and chromatographic purity assays. Our quality commitment aligns with the standards required for pharmaceutical reference materials and advanced research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.