Description

7,12-Dimethylbenz(A)Anthracene-1,2-Dihydrodiol is a high-purity dihydrodiol derivative of the polycyclic aromatic hydrocarbon (PAH) 7,12-dimethylbenz[a]anthracene (DMBA). This compound is of significant value as a key biochemical intermediate and reference standard in advanced toxicological and carcinogenesis research. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and analytical service providers for mechanistic studies on metabolic activation pathways and DNA adduct formation.

Application

• Biochemical Research Standard: Serves as a critical reference material for studying the metabolic activation pathways of polycyclic aromatic hydrocarbons (PAHs).
• Carcinogenesis Studies: Used as a precursor in the investigation of DNA adduct formation and the mechanisms of chemical carcinogenesis.
• Toxicology & Metabolism Research: Employed in in vitro and in vivo models to understand the enzymatic formation of reactive diol-epoxide intermediates.
• Analytical Method Development: Acts as a calibration standard for advanced analytical techniques like HPLC-MS and GC-MS in environmental and biological monitoring.
• Pharmaceutical R&D: Used in early-stage discovery to screen for compounds that may inhibit specific metabolic pathways involved in toxicity.

Basic Information

Product Name	7,12-Dimethylbenz(A)Anthracene-1,2-Dihydrodiol
CAS No.	68984-91-8
Molecular Formula	C20H18O2
Molecular Weight	290.36 g/mol
Synonyms	7,12-Dimethylbenz[a]anthracene-1,2-dihydrodiol; DMBA-1,2-dihydrodiol; 1,2-Dihydroxy-1,2-dihydro-7,12-dimethylbenz[a]anthracene; (+/-)-7,12-Dimethylbenz[a]anthracene-1,2-diol; 7,12-DMBA-1,2-dihydrodiol; 1,2-Dihydro-7,12-dimethylbenz[a]anthracene-1,2-diol; Benz[a]anthracene-1,2-dihydrodiol, 7,12-dimethyl-
EINECS	Contact for details

Quality Control

Our 7,12-Dimethylbenz(A)Anthracene-1,2-Dihydrodiol is manufactured under strict quality protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profiles. We adhere to ISO 9001 quality management principles, and our analytical methods are validated to meet the rigorous standards expected by the global research community.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the container to reach room temperature in a desiccator before opening to minimize moisture uptake and thermal stress. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.