Description

D(-)Prolinol is a high-purity, non-natural chiral amino alcohol derivative, serving as a critical building block in asymmetric synthesis. Its enantiomeric purity makes it an indispensable chiral auxiliary and ligand for the preparation of pharmaceuticals and advanced materials. This compound is particularly valuable for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors requiring precise stereochemical control. The product is supplied as a high-quality material, with its CAS number 68832-13-3.

Application

• Pharmaceutical Intermediates: Key chiral building block for the synthesis of active pharmaceutical ingredients (APIs), especially in antiviral and cardiovascular drug candidates.
• Asymmetric Catalysis: Used as a precursor for chiral ligands and organocatalysts in enantioselective hydrogenation, alkylation, and aldol reactions.
• Agrochemical Synthesis: Employed in the research and development of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Serves as a versatile intermediate for creating specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic & Industrial R&D: A valuable reagent for method development and exploring new synthetic pathways in organic and medicinal chemistry laboratories.

Basic Information

Product Name	D(-)Prolinol
CAS No.	68832-13-3
Molecular Formula	C₅H₁₁NO
Molecular Weight	101.15 g/mol
Synonyms	(R)-(-)-2-Pyrrolidinemethanol; (R)-(-)-Prolinol; (R)-Pyrrolidin-2-ylmethanol; D-Prolinol; (-)-Prolinol; (2R)-2-Pyrrolidinylmethanol; LGM-1115; (R)-2-(Hydroxymethyl)pyrrolidine
EINECS	Contact for details

Quality Control

Our D(-)Prolinol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assay and impurity profiling, to ensure it meets the high standards required for research and production applications. A Certificate of Analysis (COA) detailing specific results for purity, enantiomeric excess, and identity is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.