Description

Dl-Aspartic Acid (4-13C) CAS NO 68315-35-5 is a stable isotope-labeled analog of the amino acid aspartic acid, where the carbon atom at the 4-position is enriched with the carbon-13 isotope. This compound is a critical tool in advanced research and analytical chemistry, enabling precise metabolic pathway tracing, protein structure elucidation, and quantitative analysis. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for applications in drug development, metabolic studies, and as an internal standard in mass spectrometry.

Application

• Metabolic Pathway Tracing: Used as a stable isotope tracer in in vivo and in vitro studies to investigate amino acid metabolism, urea cycle function, and neurotransmitter synthesis.
• Mass Spectrometry Internal Standard: Serves as a critical internal standard for the accurate quantification of endogenous aspartic acid in complex biological matrices using LC-MS/MS and GC-MS techniques.
• NMR Spectroscopy: Employed in nuclear magnetic resonance (NMR) studies for protein structure determination and dynamics, leveraging the 13C label for enhanced signal detection and assignment.
• Pharmaceutical Research & Development: Integral in the development and testing of new drugs, particularly those targeting metabolic disorders or neurological pathways involving aspartate.
• Biochemical Research: Used in enzymatic assays and studies of enzyme kinetics where aspartic acid is a substrate or product.
• Nutritional Science Studies: Applied in research to understand the metabolic fate of dietary amino acids and their role in human physiology.

Basic Information

Product Name	Dl-Aspartic Acid (4-13C)
CAS No.	68315-35-5
Molecular Formula	C313CH7NO4
Molecular Weight	134.09 g/mol (for 13C1 labeled form)
Synonyms	(2R*,3S*)-2-Amino-3-13C-butane-1,4-dioic Acid; DL-Aspartic-4-13C Acid; (±)-Aminosuccinic-4-13C Acid; Aspartic Acid (4-13C); DL-Aspartic Acid-4-13C; 2-Aminobutanedioic-4-13C Acid; (RS)-Aminobutanedioic-4-13C Acid; Aminosuccinic-4-13C Acid
EINECS	Contact for details

Quality Control

Our Dl-Aspartic Acid (4-13C) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing to ensure high chemical purity and isotopic enrichment as specified. Key parameters verified include assay (HPLC), isotopic purity (NMR/MS), optical purity, and residual solvent content. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all test results against stringent internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent absorption of atmospheric moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 99 atom % 13C
Optical Purity (DL Ratio)	~50:50 (Racemic mixture)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.