Description

4-Methylumbelliferyl β-D-Mannopyranoside is a high-purity fluorogenic substrate specifically designed for enzymatic assays. This compound is critical for the sensitive and specific detection of mannosidase activity, a key diagnostic and research tool. It is primarily utilized by biotechnology firms, diagnostic kit manufacturers, and academic research institutions focused on glycobiology, lysosomal storage disorders, and enzyme kinetics.

Application

• Enzymatic Substrate for Mannosidase: A fluorogenic probe for the detection and quantification of α- and β-mannosidase activity in various biological samples.
• Diagnostic Assay Development: A key raw material in the manufacturing of diagnostic kits for lysosomal storage diseases such as α-mannosidosis and β-mannosidosis.
• Biochemical Research: Used in glycobiology research to study enzyme mechanisms, inhibition, and carbohydrate processing pathways.
• High-Throughput Screening (HTS): Employed in drug discovery campaigns to identify potential inhibitors or activators of mannosidase enzymes.
• Quality Control in Bioprocessing: Used to monitor glycosidase activity during the production and purification of recombinant glycoprotein therapeutics.
• Plant & Microbial Biochemistry: Applied in research to investigate mannosidase activity in plants, fungi, and bacteria.

Basic Information

Product Name	4-Methylumbelliferyl β-D-Mannopyranoside
CAS No.	67909-30-2
Molecular Formula	C16H18O9
Molecular Weight	354.31 g/mol
Synonyms	4-MU-β-D-Mannopyranoside; 4-Methylumbelliferyl-β-D-mannopyranoside; β-4-MU Mannoside; 4-Methylumbelliferyl β-D-mannoside; 7-Hydroxy-4-methylcoumarin β-D-mannopyranoside; 4-Methylumbelliferyl-β-mannoside; MUB-β-Man; 4-MU-β-Man
EINECS	Contact for details

Quality Control

Our 4-Methylumbelliferyl β-D-Mannopyranoside is manufactured under strict quality systems to ensure batch-to-batch consistency and reliability for critical research and diagnostic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and performance in standard enzymatic assays. We adhere to ISO 9001 quality management principles, and our production environment is designed to meet the exacting standards required for biochemical reagents.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry environment. For long-term storage, desiccate at -20°C. Allow the product to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Specific Rotation	Contact for details
Fluorogenic Activity	Contact for details
Solubility	Soluble in DMSO, DMF; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.