Description

Glycine-13C2 is a stable isotope-labeled analog of the fundamental amino acid glycine, where two carbon atoms are replaced with the 13C isotope. This product is essential for advanced research requiring precise metabolic pathway tracing and quantitative analysis via mass spectrometry and nuclear magnetic resonance (NMR) spectroscopy. It is a critical reagent for scientists and manufacturers in the fields of pharmaceutical development, clinical diagnostics, and nutritional research.

Application

• Metabolic Flux Analysis (MFA): Used as a tracer to study central carbon metabolism in cell cultures, tissues, and whole organisms.
• Quantitative Proteomics & Biomarker Discovery: Serves as an internal standard for the accurate quantification of proteins and metabolites in mass spectrometry-based assays.
• Drug Metabolism and Pharmacokinetics (DMPK): Employed in the development and validation of analytical methods to track the absorption, distribution, metabolism, and excretion of new drug candidates.
• NMR Spectroscopy Standards: Acts as a chemical shift reference and a starting material for synthesizing other 13C-labeled compounds for structural biology studies.
• Nutritional Research: Utilized in studies investigating amino acid turnover, protein synthesis rates, and metabolic disorders.
• Stable Isotope Labeling in Cell Culture (SILAC): A key component for heavy amino acid media to label proteins for comparative proteomics.

Basic Information

Product Name	Glycine-13C2
CAS No.	67836-01-5
Molecular Formula	¹³C₂H₅NO₂
Molecular Weight	77.05 g/mol
Synonyms	Aminoacetic acid-13C2; Glycine-13C2 (99 atom % 13C); [13C2]-Glycine; 2-Aminoacetic acid-13C2; Stable isotope-labeled glycine; NSC 7601-13C2; Glycine (U-13C2); Glycine-1,2-13C2
EINECS	Contact for details

Quality Control

Every batch of our Glycine-13C2 is produced and tested under strict quality management systems. We provide comprehensive analytical data to ensure product integrity, including isotopic enrichment (Atom % 13C), chemical purity, and absence of biological contaminants. Certificates of Analysis (COA) detailing specifications for NMR, HPLC, and MS conformity are supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a desiccated atmosphere to maintain stability and isotopic purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (Atom % 13C)	≥ 99%
Chemical Purity (Titration)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.