Description

Triolein, [Carboxyl-14C] CAS NO 67318-71-2 is a radiolabeled triglyceride where the carbon-14 isotope is specifically incorporated into the carboxyl group of the oleic acid moieties. This compound is a critical tool for metabolic and biochemical research, enabling precise tracking of lipid absorption, transport, and catabolism in biological systems. It is essential for researchers and scientists in pharmaceutical development, nutritional science, and metabolic disorder studies who require high-specific-activity tracers for in vitro and in vivo experiments.

Application

• Metabolic Pathway Tracing: Used as a radiolabeled tracer to study the digestion, absorption, and β-oxidation of unsaturated fatty acids.
• Lipoprotein Metabolism Research: Investigates the incorporation of dietary fats into chylomicrons, VLDL, and other lipoproteins.
• Drug Development & ADME Studies: Employed in Absorption, Distribution, Metabolism, and Excretion (ADME) studies for lipid-based drug formulations.
• Enzymatic Activity Assays: Serves as a substrate for lipases, esterases, and other lipid-metabolizing enzymes to measure kinetic parameters.
• Nutritional Science: Tracks the fate of dietary oleic acid in animal models to understand energy metabolism and obesity.
• Cell Biology: Studies lipid droplet formation, intracellular lipid trafficking, and membrane lipid dynamics.

Basic Information

Product Name	Triolein, [Carboxyl-14C]
CAS No.	67318-71-2
Molecular Formula	C57H10414C3O6 *
Molecular Weight	~885.4 g/mol (unlabeled) *
Synonyms	Glycerol Trioleate, [carboxyl-14C]; [1-14C]Oleoyl Triolein; 1,2,3-Tri(cis-9-octadecenoyl)glycerol (labeled); Trioleoyl-1-14C-glycerol; Glyceryl trioleate-14C; Oleic Acid Triglyceride-14C; TO-14C; Radiolabeled Triolein
EINECS	Contact for details

* Exact molecular weight depends on the specific activity and position of the 14C label. Contact us for the exact specification of your batch.

Quality Control

Every batch of Triolein, [Carboxyl-14C] is manufactured and analyzed under strict quality control protocols to ensure radiochemical purity, chemical purity, and specific activity. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing specific activity, radiochemical purity (by HPLC or TLC), chemical purity, and solvent composition are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize radiolytic decomposition and oxidation. For long-term storage, solutions are recommended. Follow all applicable radiation safety regulations for handling and disposal.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil or solution
Identification (IR/NMR)	Conforms to structure
Specific Activity	Customizable (e.g., 50-60 mCi/mmol)
Radiochemical Purity (HPLC)	≥ 95%
Chemical Purity (HPLC)	≥ 98%
Solvent	Toluene, Ethanol, or as specified
Concentration	Customizable (e.g., 0.1 mCi/mL)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.