Description

Testosterone, [1,2,6,7-3H] CAS NO 67308-98-9 is a high-specific-activity, tritium-labeled derivative of the primary male sex hormone, testosterone. This radiolabeled compound is an indispensable tool for advanced research, enabling precise tracking and quantification of testosterone in complex biological systems. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and clinical diagnostic developers for metabolic studies, receptor binding assays, and the development of analytical methods.

Application

• Biomedical Research & Drug Discovery: Used as a tracer in receptor binding assays and competitive binding studies to screen for new androgen receptor modulators and endocrine-disrupting compounds.
• Metabolic Pathway Analysis: Enables the detailed study of testosterone's absorption, distribution, metabolism, and excretion (ADME) profiles in preclinical models.
• Clinical Diagnostics Development: Serves as a critical reference standard and tracer in the development and validation of high-sensitivity radioimmunoassays (RIA) and other ligand-binding assays for hormone level quantification.
• Endocrinology Studies: Facilitates research into androgen synthesis, steroidogenesis, and the physiological and pathological roles of testosterone in development, aging, and disease states.
• Environmental Toxicology: Employed in studies assessing the impact of environmental contaminants on the endocrine system by tracking androgen receptor interaction and disruption.

Basic Information

Product Name	Testosterone, [1,2,6,7-3H]
CAS No.	67308-98-9
Molecular Formula	C19H28O2 (³H-labeled)
Molecular Weight	~288.4 g/mol (varies with specific activity)
Synonyms	17β-Hydroxyandrost-4-en-3-one, [1,2,6,7-³H]; [³H]-Testosterone; Tritiated Testosterone; Androst-4-en-17β-ol-3-one, tritium labeled; Testosterone-1,2,6,7-³H; NSC-9700 (³H-labeled); 4-Androsten-17β-ol-3-one, [1,2,6,7-³H]
EINECS	Contact for details

Quality Control

Every batch of Testosterone, [1,2,6,7-3H] is manufactured and analyzed under strict quality systems. Radiochemical purity and specific activity are determined using validated methods such as HPLC with radiometric detection and liquid scintillation counting (LSC). Certificates of Analysis (COA) are provided, detailing specific activity (Ci/mmol or GBq/mmol), radiochemical purity, chemical purity, and solvent composition. Our quality commitment ensures consistency and reliability for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store the product in the original solvent (as specified on the label) at or below -20°C. Avoid repeated freeze-thaw cycles. All handling must be performed in accordance with local radiation safety regulations for tritium.

Specification

Item	Specification
Appearance	Clear, colorless to slightly yellow solution
Specific Activity	70-110 Ci/mmol (2.6-4.1 TBq/mmol) [Typical]
Radiochemical Purity	≥ 97% (by HPLC)
Chemical Purity	≥ 95% (by HPLC, UV detection)
Concentration	1 mCi/mL (37 MBq/mL) [Typical]
Solvent	Ethanol or Toluene/Ethanol mixture
Identification	Co-chromatography with reference standard (HPLC)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.