Description

3-(2-Chloro-10,11-Dihydro-5H-Dibenzo[A,D]Cyclohepten-5-Ylidene)-N,n-Dimethyl-1-Propanamine is a high-purity, synthetically derived organic compound that serves as a crucial advanced intermediate in modern pharmaceutical research and development. Its complex tricyclic structure makes it a valuable building block for the synthesis of novel therapeutic agents targeting the central nervous system. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical and fine chemical industries for creating potential drug candidates and reference standards.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel tricyclic antidepressant analogs and other neuroactive compounds.
• Active Pharmaceutical Ingredient (API) Development: Used in research for developing new chemical entities (NCEs) with potential therapeutic applications.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to optimize pharmacological profiles.
• Process Chemistry: Used for scaling up synthetic routes and optimizing manufacturing processes for complex organic molecules.
• Academic Research: A valuable compound for universities and research institutes studying organic synthesis methodologies and neuropharmacology.

Basic Information

Item	Details
Product Name	3-(2-Chloro-10,11-Dihydro-5H-Dibenzo[A,D]Cyclohepten-5-Ylidene)-N,n-Dimethyl-1-Propanamine
CAS No.	67195-22-6
Molecular Formula	C20H22ClN
Molecular Weight	311.85 g/mol
Synonyms	2-Chloro-10,11-dihydro-N,N-dimethyl-5H-dibenzo[a,d]cycloheptene-5-propanamine; 2-Chloroprotriptyline; 2-Chloro-N,N-dimethyl-10,11-dihydro-5H-dibenzo[a,d]cycloheptene-δ5,γ-propylamine; NSC 169865; Protriptyline Impurity; 5-(3-Dimethylaminopropylidene)-2-chloro-10,11-dihydro-5H-dibenzo[a,d]cycloheptene
EINECS	Contact for details

Quality Control

Our 3-(2-Chloro-10,11-Dihydro-5H-Dibenzo[A,D]Cyclohepten-5-Ylidene)-N,n-Dimethyl-1-Propanamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to GMP-compliant practices ensures the material is suitable for demanding applications in pharmaceutical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.