Description

2-Cyanoacetamide, [2-14C] is a carbon-14 labeled isotopologue of the versatile organic building block, 2-cyanoacetamide. This radiolabeled compound is essential for conducting precise metabolic and pharmacokinetic studies, enabling researchers to track the fate of molecules within complex biological systems. It is a critical reagent for scientists in pharmaceutical R&D, agrochemical development, and biochemical research who require high-specific-activity tracers for autoradiography, ADME (Absorption, Distribution, Metabolism, and Excretion) studies, and pathway elucidation.

Application

• Tracer in Pharmaceutical Metabolism Studies: Used as a labeled precursor or intermediate to synthesize radiolabeled drug candidates for tracking their absorption, distribution, and excretion profiles.
• Agrochemical Research: Employed in the development and environmental fate studies of new pesticides and herbicides to understand degradation pathways and metabolite identification.
• Biochemical Pathway Analysis: Serves as a tool to investigate biosynthetic pathways in microorganisms or plants, particularly those involving nitrile or amide functional groups.
• Organic Synthesis Intermediate: Acts as a building block for the synthesis of more complex 14C-labeled heterocyclic compounds, such as pyrimidines and purines, for research purposes.
• Quality Control & Reference Standard: Can be utilized as an internal standard in advanced analytical techniques like LC-MS for quantitative analysis in complex matrices.

Basic Information

Product Name	2-Cyanoacetamide, [2-14C]
CAS No.	67120-90-5
Molecular Formula	C3H414CNO
Molecular Weight	~85.05 g/mol (based on 12C; exact mass varies with specific activity)
Synonyms	2-Cyanoacetamide-2-14C; [2-14C]Cyanoacetamide; Acetamide, 2-cyano-2-14C-; 3-Oxopropanenitrile-3-14C; Malononitrile monoamide-2-14C; Cyanomethylcarboxamide-2-14C; NSC 8426 (labeled)
EINECS	Contact for details

Quality Control

Every batch of our 2-Cyanoacetamide, [2-14C] is manufactured and analyzed under strict quality systems to ensure high chemical and radiochemical purity, specific activity, and stability. Our products undergo rigorous quality testing, including HPLC, NMR, and mass spectrometry, to ensure compliance with the stringent requirements of research and development. A comprehensive Certificate of Analysis (COA) detailing chemical purity, radiochemical purity, specific activity, solvent content, and analytical chromatograms is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. For long-term storage, solutions may be kept at or below -20°C. Follow all applicable local and international regulations for the safe handling and storage of radioactive materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Chemical Purity (HPLC)	≥ 98%
Radiochemical Purity (HPLC)	≥ 97%
Specific Activity	Customizable (mCi/mmol range)
Solvent (Residual)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.