Description

7-Oxyisotithocholic Acid is a high-purity bile acid derivative with significant research and pharmaceutical development potential. This compound serves as a critical intermediate and reference standard in the synthesis of novel therapeutic agents and biochemical studies. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on metabolic and liver-related drug discovery.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel bile acid analogs and hepatoprotective agents.
• Biochemical Research: Used as a reference standard and probe in studies of bile acid metabolism, liver function, and membrane transport mechanisms.
• Metabolic Pathway Analysis: Employed in in-vitro and in-vivo studies to investigate the role of specific bile acid derivatives in metabolic disorders.
• Analytical Standard: Serves as a high-purity calibration standard for HPLC, LC-MS, and other analytical methods in quality control and research laboratories.
• Drug Discovery: A valuable starting material for medicinal chemistry programs targeting nuclear receptors like FXR (Farnesoid X receptor).
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic chemistry, stereochemistry, and natural product derivatives.

Basic Information

Product Name	7-Oxyisotithocholic Acid
CAS No.	67008-26-8
Molecular Formula	C₂₄H₄₀O₅
Molecular Weight	408.57 g/mol
Synonyms	7-Oxoisotithocholic Acid; 3α,7α-Dihydroxy-5β-cholan-24-oic Acid 7-Oxo Derivative; Isotithocholic Acid 7-Oxide; 7-Ketoisotithocholic Acid; 5β-Cholan-24-oic acid, 3α,7α-dihydroxy-, 7-oxo-; (3α,5β,7α)-3,7-Dihydroxycholan-24-oic acid 7-one
EINECS	Contact for details

Quality Control

Our 7-Oxyisotithocholic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis to ensure it meets exacting standards for research and development use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.