Description

Bicifadine CAS NO 66504-75-4 is a synthetic organic compound belonging to the class of norepinephrine-dopamine reuptake inhibitors (NDRIs). This compound is of significant interest in pharmaceutical research and development due to its unique pharmacological profile. It is primarily utilized by research institutions, pharmaceutical companies, and contract development and manufacturing organizations (CDMOs) engaged in the synthesis of novel therapeutic agents targeting the central nervous system.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of advanced active pharmaceutical ingredients (APIs) for research purposes.
• Neuroscience Research: Used as a reference standard or tool compound in preclinical studies investigating neurotransmitter reuptake mechanisms.
• Analytical Standard: Employed for method development, calibration, and quality control in analytical laboratories using techniques like HPLC and LC-MS.
• Chemical Synthesis: Acts as a precursor for the development of novel chemical entities with potential analgesic or psychostimulant properties.
• Biochemical Assays: Utilized in in vitro assays to study binding affinity and inhibition potency at monoamine transporters.

Basic Information

Product Name	Bicifadine
CAS No.	66504-75-4
Molecular Formula	C17H25NO
Molecular Weight	259.39 g/mol
Synonyms	(±)-1-(4-Methylphenyl)-3-azabicyclo[3.1.0]hexane; Bicifadine Hydrochloride (salt form); (±)-Bicifadine; DW-224; Loxapine related compound; 3-Azabicyclo[3.1.0]hexane, 1-(4-methylphenyl)-
EINECS	Contact for details

Quality Control

Our Bicifadine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and support our products with detailed Certificates of Analysis (COA) that include results from HPLC, NMR, and other relevant spectroscopic methods. Specifications are aligned with research-grade material standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.