Description

(2R,3R)-(+)-2,3-Butanediamine Dihydrochloride is a high-purity chiral diamine salt, serving as a critical building block in asymmetric synthesis and pharmaceutical development. Its defined stereochemistry provides essential control over the three-dimensional structure of target molecules, enabling the production of enantiomerically pure compounds. This material is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for the development of active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly in antiviral, antibiotic, and cardiovascular drug research.
• Asymmetric Catalyst Ligand Precursor: Used to synthesize chiral ligands for transition metal catalysts in enantioselective hydrogenation, oxidation, and C-C bond formation reactions.
• Agrochemical Synthesis: Employed in the development of chiral herbicides, fungicides, and plant growth regulators where specific stereochemistry impacts biological activity.
• Fine Chemical & Specialty Polymer Production: Serves as a monomer or cross-linking agent for creating polymers with specific optical or mechanical properties.
• Bioconjugation & Peptide Mimetics: Utilized in bioconjugation chemistry and the design of peptide analogs and enzyme inhibitors for biochemical research.
• Academic & Process Chemistry Research: A valuable reagent for methodological development in organic synthesis and scale-up process optimization in academic and industrial R&D labs.

Basic Information

Product Name	(2R,3R)-(+)-2,3-Butanediamine Dihydrochloride
CAS No.	66427-25-6
Molecular Formula	C4H12N2·2HCl
Molecular Weight	161.07 g/mol
Synonyms	(2R,3R)-2,3-Diaminobutane Dihydrochloride; (2R,3R)-(+)-2,3-Diaminobutane Dihydrochloride; (R,R)-2,3-Diaminobutane Dihydrochloride; D-2,3-Diaminobutane Dihydrochloride; (2R,3R)-Butane-2,3-diamine Dihydrochloride; (2R,3R)-1,2-Diaminobutane Dihydrochloride; (2R,3R)-Tetramethylenediamine Dihydrochloride
EINECS	Contact for details

Quality Control

Our (2R,3R)-(+)-2,3-Butanediamine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and production. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.