Description

14-Hydroxy-3β,2α-[[(2S,6R)-Tetrahydro-3,5-Dihydroxy-6-Methyl-4-Oxo-2H-Pyran-2,3-Diyl]Bis(Oxy)]-5α-Card-20(22)-Enolide is a high-purity, structurally complex cardenolide derivative. This compound is of significant interest for its potential as a key intermediate or reference standard in advanced pharmaceutical research and development. It is primarily sought by R&D laboratories and manufacturers in the life sciences sector focusing on cardiovascular therapeutics and novel bioactive natural product derivatives.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthetic pathways for novel cardioactive steroid drugs.
• Reference Standard: Used as a high-purity analytical standard in quality control (QC) and research laboratories for method development and validation.
• Biochemical Research: Employed in studies investigating the structure-activity relationships (SAR) of cardenolides and their interaction with biological targets like Na+/K+-ATPase.
• Active Pharmaceutical Ingredient (API) Development: Acts as a precursor in the development and scale-up of potential new active ingredients for therapeutic applications.

Basic Information

Item	Details
Product Name	14-Hydroxy-3β,2α-[[(2S,6R)-Tetrahydro-3,5-Dihydroxy-6-Methyl-4-Oxo-2H-Pyran-2,3-Diyl]Bis(Oxy)]-5α-Card-20(22)-Enolide
CAS No.	66419-08-7
Molecular Formula	C29H42O10
Molecular Weight	550.64 g/mol
Synonyms	14-Hydroxy-3β,2α-[[(2S,6R)-Tetrahydro-3,5-dihydroxy-6-methyl-4-oxo-2H-pyran-2,3-diyl]bis(oxy)]-5α-card-20(22)-enolide; 3β,2α-Bis-O-(2,6-dideoxy-3-O-methyl-α-L-ribo-hexopyranosyl-4-ulosyl)-14-hydroxy-5α-card-20(22)-enolide; A derivative of Cardenolide; 14-Hydroxycardenolide glycoside derivative
EINECS	Contact for details

Quality Control

Our 14-Hydroxy-3β,2α-[[(2S,6R)-Tetrahydro-3,5-Dihydroxy-6-Methyl-4-Oxo-2H-Pyran-2,3-Diyl]Bis(Oxy)]-5α-Card-20(22)-Enolide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets exacting research-grade specifications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.