Description

(R)-1-Methyl-2-Aminomethylpyrrolidine CAS NO 66411-53-8 is a high-purity chiral amine building block of significant importance in asymmetric synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecules with defined stereochemistry. This compound is primarily needed by pharmaceutical R&D and fine chemical manufacturers for applications in active pharmaceutical ingredient (API) development and advanced material science.

Application

• As a key chiral ligand or auxiliary in asymmetric catalysis for pharmaceutical synthesis.
• As a crucial building block in the research and development of novel Active Pharmaceutical Ingredients (APIs).
• For the synthesis of complex natural products and fine chemicals requiring high stereoselectivity.
• In the preparation of advanced materials and specialty polymers where chirality imparts specific properties.
• As an intermediate in agrochemical research for developing enantiomerically pure compounds.
• Utilized in academic and industrial research for methodological studies in organic synthesis.

Basic Information

Product Name	(R)-1-Methyl-2-Aminomethylpyrrolidine
CAS No.	66411-53-8
Molecular Formula	C7H16N2
Molecular Weight	128.22 g/mol
Synonyms	(R)-1-Methyl-2-(aminomethyl)pyrrolidine; (R)-N-Methyl-2-(aminomethyl)pyrrolidine; (2R)-1-Methyl-2-(aminomethyl)pyrrolidine; (R)-2-(Aminomethyl)-1-methylpyrrolidine; (R)-AMPY; (R)-1-Methylpyrrolidine-2-methanamine; (R)-N-Methylprolinamine; (R)-N-Methyl-2-pyrrolidinemethanamine
EINECS	Contact for details

Quality Control

Our (R)-1-Methyl-2-Aminomethylpyrrolidine is manufactured under strict quality control protocols to ensure high chemical and chiral purity, meeting the stringent requirements of pharmaceutical intermediates. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles. We adhere to cGMP principles where applicable to support regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.