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2-Amino-9-[(2R,4S,5S)-4-Amino-5-(Hydroxymethyl)Oxolan-2-Yl]-3H-Purin-6-One CAS NO 66323-49-7


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CAS No.:66323-49-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-Amino-9-[(2R,4S,5S)-4-Amino-5-(Hydroxymethyl)Oxolan-2-Yl]-3H-Purin-6-One is a high-purity nucleoside analog of significant importance in advanced pharmaceutical research and development. This compound serves as a critical building block and reference standard for the synthesis of novel antiviral and anticancer agents. It is primarily needed by research institutions, pharmaceutical development companies, and fine chemical manufacturers focused on nucleoside-based therapeutics.

Application

  • Pharmaceutical Intermediate: A key precursor in the synthesis of novel antiviral drugs, particularly those targeting viral polymerases.
  • Biochemical Research: Used as a reference standard and substrate in enzymatic studies and metabolic pathway research.
  • Anticancer Agent Development: Investigated as a core scaffold for developing nucleoside analogs that inhibit cancer cell proliferation.
  • Antiviral Drug Discovery: Serves as a critical building block for creating next-generation treatments for viral infections.
  • Process Chemistry: Employed in the scale-up and optimization of synthetic routes for complex nucleoside pharmaceuticals.
  • Analytical Standard: Provides a high-purity benchmark for quality control (HPLC, MS) in pharmaceutical manufacturing.

Basic Information

Product Name 2-Amino-9-[(2R,4S,5S)-4-Amino-5-(Hydroxymethyl)Oxolan-2-Yl]-3H-Purin-6-One
CAS No. 66323-49-7
Molecular Formula C10H14N6O4
Molecular Weight 282.26 g/mol
Synonyms 2-Amino-9-[(2R,4S,5S)-4-Amino-5-(hydroxymethyl)tetrahydrofuran-2-yl]-1,9-dihydro-6H-purin-6-one; 2-Aminoadenosine; 2-Amino-9-β-D-ribofuranosyl-9H-purin-6-ol; Cordycepin analog; 2-NH2-Ado; 2-Amino-9-(β-D-ribofuranosyl)adenine; 2-Aminoadenosine (nucleoside); 2-Amino-ara-A
EINECS Contact for details

Quality Control

Our 2-Amino-9-[(2R,4S,5S)-4-Amino-5-(Hydroxymethyl)Oxolan-2-Yl]-3H-Purin-6-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to reference spectrum
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 10 ppm
Specific Rotation Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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