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2-Amino-9-[(2R,4S,5S)-4-Amino-5-(Hydroxymethyl)Oxolan-2-Yl]-3H-Purin-6-One CAS NO 66323-49-7
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CAS No.:66323-49-7
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
2-Amino-9-[(2R,4S,5S)-4-Amino-5-(Hydroxymethyl)Oxolan-2-Yl]-3H-Purin-6-One is a high-purity nucleoside analog of significant importance in advanced pharmaceutical research and development. This compound serves as a critical building block and reference standard for the synthesis of novel antiviral and anticancer agents. It is primarily needed by research institutions, pharmaceutical development companies, and fine chemical manufacturers focused on nucleoside-based therapeutics.
Application
- Pharmaceutical Intermediate: A key precursor in the synthesis of novel antiviral drugs, particularly those targeting viral polymerases.
- Biochemical Research: Used as a reference standard and substrate in enzymatic studies and metabolic pathway research.
- Anticancer Agent Development: Investigated as a core scaffold for developing nucleoside analogs that inhibit cancer cell proliferation.
- Antiviral Drug Discovery: Serves as a critical building block for creating next-generation treatments for viral infections.
- Process Chemistry: Employed in the scale-up and optimization of synthetic routes for complex nucleoside pharmaceuticals.
- Analytical Standard: Provides a high-purity benchmark for quality control (HPLC, MS) in pharmaceutical manufacturing.
Basic Information
| Product Name | 2-Amino-9-[(2R,4S,5S)-4-Amino-5-(Hydroxymethyl)Oxolan-2-Yl]-3H-Purin-6-One |
| CAS No. | 66323-49-7 |
| Molecular Formula | C10H14N6O4 |
| Molecular Weight | 282.26 g/mol |
| Synonyms | 2-Amino-9-[(2R,4S,5S)-4-Amino-5-(hydroxymethyl)tetrahydrofuran-2-yl]-1,9-dihydro-6H-purin-6-one; 2-Aminoadenosine; 2-Amino-9-β-D-ribofuranosyl-9H-purin-6-ol; Cordycepin analog; 2-NH2-Ado; 2-Amino-9-(β-D-ribofuranosyl)adenine; 2-Aminoadenosine (nucleoside); 2-Amino-ara-A |
| EINECS | Contact for details |
Quality Control
Our 2-Amino-9-[(2R,4S,5S)-4-Amino-5-(Hydroxymethyl)Oxolan-2-Yl]-3H-Purin-6-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Keep away from strong oxidizing agents.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (IR) | Conforms to reference spectrum |
| Identification (HPLC) | Retention time matches reference standard |
| Purity (HPLC) | ≥ 98.0% |
| Water Content (KF) | ≤ 1.0% |
| Residue on Ignition | ≤ 0.1% |
| Heavy Metals | ≤ 10 ppm |
| Specific Rotation | Contact for details |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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