Description

(R)-Bis[[[2-(Hydroxyphenyl)-1-Methyl]Ethyl]Ammonium] [R-(R*,R*)]-Tartrate is a high-purity chiral ammonium tartrate salt, distinguished by its specific stereochemistry. This compound is valued for its role as a key intermediate and resolving agent in the synthesis of enantiomerically pure pharmaceuticals and fine chemicals. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise stereochemical control. The product is supplied to meet the stringent quality demands of process development and commercial-scale production.

Application

• Chiral Resolution Agent: Used for the separation of racemic mixtures of acids or other compounds via diastereomeric salt formation.
• Pharmaceutical Intermediate: Serves as a critical building block in the asymmetric synthesis of active pharmaceutical ingredients (APIs), particularly those targeting neurological and cardiovascular diseases.
• Catalyst Ligand Precursor: Employed in the development of chiral catalysts for asymmetric hydrogenation and other stereoselective transformations.
• Agrochemical Synthesis: Used in the production of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Analytical Standard: Functions as a reference standard in HPLC and LC-MS methods for quality control and method validation in chiral analysis.
• Academic & Process Research: Essential for research in organic chemistry, medicinal chemistry, and process optimization in both academic and industrial R&D settings.

Basic Information

Item	Details
Product Name	(R)-Bis[[[2-(Hydroxyphenyl)-1-Methyl]Ethyl]Ammonium] [R-(R*,R*)]-Tartrate
CAS No.	66068-91-5
Molecular Formula	C26H36N2O8
Molecular Weight	504.58 g/mol
Synonyms	(R,R)-DBTA Salt; (R)-1,1'-Binaphthyl-2,2'-diyl Hydrogenphosphate Ammonium Salt (related derivative); (R)-Bis(1-phenylethyl)ammonium (R,R)-tartrate; (R)-α-Methylbenzylammonium (R,R)-tartrate; (R)-PEA (R,R)-Tartrate; Chiral Ammonium Tartrate Salt; (R)-1-Phenylethylammonium (R,R)-tartrate; (R)-Bis(α-methylbenzyl)ammonium (R,R)-tartrate
EINECS	Contact for details

Quality Control

Our (R)-Bis[[[2-(Hydroxyphenyl)-1-Methyl]Ethyl]Ammonium] [R-(R*,R*)]-Tartrate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity assay and identification of key impurities, to ensure it meets the high standards required for synthetic applications. A Certificate of Analysis (COA) detailing purity, enantiomeric excess, and other critical parameters is provided with every shipment. We support compliance with cGMP and ISO guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.