Description

3-Hydroxymethyl-4-Oxa-1-Azabicyclo[3.2.0]Heptan-7-One CAS NO 66036-39-3 is a specialized bicyclic lactam compound that serves as a crucial advanced intermediate in organic synthesis. Its unique fused ring structure containing both oxygen and nitrogen makes it a valuable building block for constructing complex molecules with high precision. This compound is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs), particularly within the β-lactam antibiotic and other heterocyclic therapeutic classes.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of novel β-lactam antibiotics and other nitrogen-oxygen heterocyclic drugs.
• Organic Synthesis Building Block: Used for constructing complex fused-ring systems in medicinal chemistry and process development.
• Academic & Industrial Research: Serves as a critical reagent in chemical libraries for screening and developing new therapeutic candidates.
• Process Chemistry: Employed in route scouting and scale-up synthesis for advanced pharmaceutical intermediates.
• Fine Chemical Production: Utilized in the manufacture of high-value, low-volume specialty chemicals with specific biological activity.

Basic Information

Product Name	3-Hydroxymethyl-4-Oxa-1-Azabicyclo[3.2.0]Heptan-7-One
CAS No.	66036-39-3
Molecular Formula	C7H9NO3
Molecular Weight	155.15 g/mol
Synonyms	3-(Hydroxymethyl)-4-oxa-1-azabicyclo[3.2.0]heptan-7-one; 4-Oxa-1-azabicyclo[3.2.0]heptan-7-one, 3-(hydroxymethyl)-; 3-Hydroxymethyl-4-oxa-1-azabicyclo[3.2.0]heptan-7-one; Bicyclic β-lactam intermediate; Oxapenam derivative
EINECS	Contact for details

Quality Control

Our 3-Hydroxymethyl-4-Oxa-1-Azabicyclo[3.2.0]Heptan-7-One is produced under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. All materials are subjected to rigorous analytical testing, including HPLC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.