Description

Di-o-Toluoyl-L-Tartaric Acid is a high-purity chiral resolving agent and a key intermediate in asymmetric synthesis. This compound is valued for its ability to separate enantiomers of amines, amino acids, and other pharmaceutically relevant compounds, ensuring optical purity in final products. It is essential for manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require precise chiral resolution and synthesis capabilities.

Application

• Chiral Resolution Agent: For the separation of racemic mixtures of amines, amino alcohols, and other basic pharmaceuticals.
• Asymmetric Synthesis Intermediate: Used in the synthesis of enantiomerically pure compounds for active pharmaceutical ingredients (APIs).
• Pharmaceutical Manufacturing: A critical reagent in the production of single-enantiomer drugs to ensure efficacy and reduce side effects.
• Agrochemical Synthesis: Employed in creating chiral pesticides and herbicides with targeted activity.
• Catalyst and Ligand Preparation: Serves as a precursor for chiral catalysts used in stereoselective reactions.
• Analytical Chemistry: Used as a chiral selector in chromatography for analytical method development and quality control.
• Fine Chemical Production: A building block for complex, high-value specialty chemicals.
• Academic and R&D: Utilized in research laboratories for method development and studying chiral interactions.

Basic Information

Product Name	Di-o-Toluoyl-L-Tartaric Acid
CAS No.	65259-83-8
Molecular Formula	C22H22O8
Molecular Weight	414.41 g/mol
Synonyms	DOTTA; (2R,3R)-2,3-Bis(2-methylbenzoyloxy)succinic acid; L-Di-o-Toluoyltartaric Acid; Di-(2-methylbenzoyl)-L-tartaric acid; (2R,3R)-Di-o-toluoyl tartaric acid; o-Toluoyl-L-tartaric Acid; (-)-Di-o-Toluoyl-L-tartaric Acid
EINECS	Contact for details

Quality Control

Our Di-o-Toluoyl-L-Tartaric Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity and chemical assay, to ensure it meets the high standards required for chiral resolution and synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, specific rotation, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Specific Rotation [α]	-120° to -130° (c=1 in CHCl3)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.