Description

2-Bromo-5-Fluoro-4-Methoxybenzoic Acid is a high-purity, multi-functional halogenated benzoic acid derivative that serves as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it an invaluable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the bromo and fluoro substituents enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for synthesizing fluorinated aromatic cores used in electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer Chemistry: Acts as a monomer or modifying agent for creating specialty polymers with specific thermal, optical, or chemical resistance properties.
• Chemical Research & Development: Essential reagent in academic and industrial R&D for exploring new coupling reactions, synthesizing complex ligands, and developing novel fluorination methodologies.
• Dye & Pigment Industry: Intermediate for manufacturing specialized fluorinated dyes and pigments that offer improved lightfastness and color properties.

Basic Information

Product Name	2-Bromo-5-Fluoro-4-Methoxybenzoic Acid
CAS No.	64695-99-4
Molecular Formula	C8H6BrFO3
Molecular Weight	249.04 g/mol
Synonyms	4-Methoxy-2-bromo-5-fluorobenzoic Acid; 5-Fluoro-2-bromo-4-methoxybenzoic Acid; 2-Bromo-5-fluoro-4-methoxybenzoic acid; Benzoic acid, 2-bromo-5-fluoro-4-methoxy-; 64695-99-4; 2-Br-5-F-4-MeO-BA
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Fluoro-4-Methoxybenzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.