Description

9Alpha,11,15S-Trihydroxy-Thrombox-13E-En-1-Oic Acid is a high-purity thromboxane A2 (TXA2) analog, a key intermediate in prostaglandin and thromboxane research. This compound is critical for studying platelet aggregation, vasoconstriction, and related cardiovascular and inflammatory pathways. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and manufacturers of advanced biochemical reagents for developing novel therapeutic agents and diagnostic tools.

Application

• Pharmaceutical Research & Development: Serves as a crucial reference standard and synthetic intermediate in the development of anti-thrombotic and cardiovascular drugs.
• Biochemical Assay Development: Used as a precise calibrant and active component in enzyme-linked immunosorbent assays (ELISAs) and other in vitro diagnostic tests targeting thromboxane pathways.
• Academic & Clinical Research: Enables fundamental studies on the role of thromboxanes in hemostasis, inflammation, bronchoconstriction, and other physiological processes.
• Metabolite Synthesis: Acts as a key precursor for the synthesis of other thromboxane metabolites and structurally related eicosanoids for biological evaluation.
• Quality Control & Standardization: Employed as a high-purity analytical standard in QC laboratories to ensure the accuracy and consistency of related pharmaceutical products and research materials.

Basic Information

Product Name	9Alpha,11,15S-Trihydroxy-Thrombox-13E-En-1-Oic Acid
CAS No.	64626-32-0
Molecular Formula	C₂₀H₃₂O₆
Molecular Weight	368.47 g/mol
Synonyms	9α,11,15S-Trihydroxythromboxa-13E-en-1-oic Acid; Thromboxane B3; TXB3; 9α,11,15-Trihydroxythromboxa-5,13-dien-1-oic Acid; (5Z,9α,13E,15S)-9,11,15-Trihydroxythromboxa-5,13-dien-1-oic Acid; 9,11,15-Trihydroxythromboxa-5,13-dien-1-oic Acid; Thromboxane A2 Metabolite Analog
EINECS	Contact for details

Quality Control

Our 9Alpha,11,15S-Trihydroxy-Thrombox-13E-En-1-Oic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent high purity.

Storage

Preserve in a tightly closed container, protected from light. For long-term storage, keep at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Store away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.