Description

(R)-(-)-Denopamine Hydrochloride is a high-purity, enantiomerically pure pharmaceutical intermediate and active pharmaceutical ingredient (API). This compound is a selective β-1 adrenergic receptor agonist, making it a critical building block in cardiovascular research and drug development. It is primarily utilized by pharmaceutical manufacturers and research institutions for the synthesis of novel therapeutics and as a reference standard in analytical studies.

Application

• Key intermediate in the synthesis of advanced cardiovascular drugs and β-1 adrenergic agonists.
• Active Pharmaceutical Ingredient (API) for formulation development in preclinical and clinical studies.
• High-purity reference standard for quality control and analytical method development (HPLC, LC-MS).
• Biochemical research tool for studying cardiac muscle contractility and β-1 adrenergic receptor mechanisms.
• Starting material for the preparation of deuterated or other isotopically labeled analogs for metabolic studies.
• Used in pharmacological screening and assay development within drug discovery pipelines.

Basic Information

Product Name	(R)-(-)-Denopamine Hydrochloride
CAS No.	64299-19-0
Molecular Formula	C12H18N2O2 • HCl
Molecular Weight	258.74 g/mol
Synonyms	(R)-Denopamine HCl; (-)-Denopamine Hydrochloride; (R)-(-)-1-(4-Hydroxyphenyl)-2-[(3,4-dimethoxyphenethyl)amino]ethanol Hydrochloride; TA-064; (R)-TA-064; Denopamine (R-enantiomer) Hydrochloride; (R)-4'-[2-Hydroxy-3-[(3,4-dimethoxyphenethyl)amino]propyl]acetophenone Hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-(-)-Denopamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting specifications suitable for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting results for key parameters including chiral purity, assay, and related substances.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (R-enantiomer)
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.