Description

Dl-Phenylalanine-2-13C CAS NO 64193-01-7 is a stable isotope-labeled analog of the essential amino acid phenylalanine, where the carbon atom at the 2-position is enriched with the carbon-13 isotope. This labeled compound is a critical tool in advanced research and development, enabling precise metabolic pathway tracing, quantitative proteomics, and pharmacokinetic studies. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and manufacturers of diagnostic agents and internal standards for mass spectrometry.

Application

• Biomedical Research: As a tracer in metabolic flux analysis and protein turnover studies using NMR or LC-MS.
• Pharmaceutical Development: For the synthesis of isotopically labeled drug candidates to study absorption, distribution, metabolism, and excretion (ADME).
• Clinical Diagnostics: Used as an internal standard in quantitative mass spectrometry for accurate measurement of phenylalanine and related metabolites in patient samples.
• Nutritional Science: Research into amino acid metabolism, protein synthesis, and disorders like phenylketonuria (PKU).
• Proteomics & Metabolomics: Enables accurate quantification and identification in complex biological samples.
• Chemical Synthesis: A building block for synthesizing more complex 13C-labeled peptides, proteins, or organic molecules.

Basic Information

Product Name	Dl-Phenylalanine-2-13C
CAS No.	64193-01-7
Molecular Formula	C9H11NO2 (with 13C at C-2)
Molecular Weight	~166.19 g/mol (13C adjusted)
Synonyms	(±)-2-Amino-3-phenylpropanoic acid-2-13C; DL-α-Amino-β-phenylpropionic acid-2-13C; DL-β-Phenylalanine-2-13C; DL-Phenylalanine-2-13C; Phenylalanine-2-13C (racemic); 13C Labeled DL-Phenylalanine; Racemic Phenylalanine-2-13C; FEMA 3585 (unlabeled reference)
EINECS	Contact for details

Quality Control

Our Dl-Phenylalanine-2-13C is produced under strict quality management protocols. Each batch is characterized to ensure high chemical purity and isotopic enrichment, typically exceeding 99% chemical purity and 99 atom % 13C. Certificates of Analysis (COA) are provided, detailing results for assay, isotopic enrichment, optical rotation, residual solvents, and identification (IR, NMR). We support compliance with relevant research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure and labeling position
Assay (HPLC)	≥ 99.0%
Isotopic Enrichment (MS)	≥ 99 atom % 13C
Optical Rotation	~0° (racemic mixture)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.