Description

10,11-Dihydro-N,n-Dimethyl-2-[(4-Methyl-1-Piperazinyl)Methyl]-5H-Dibenz[B,F]Azepine-5-Propan-1-Amine CAS NO 64097-65-0 is a high-purity, complex organic compound belonging to the dibenzazepine class, serving as a critical pharmaceutical intermediate and research chemical. Its value lies in its specific molecular architecture, which is essential for synthesizing advanced active pharmaceutical ingredients (APIs) and for use in pharmacological and biochemical research. This product is primarily needed by pharmaceutical manufacturers, contract research organizations (CROs), and academic research laboratories focused on central nervous system (CNS) drug discovery and development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel psychotropic and neuroactive drug candidates.
• Research & Development: Used in preclinical studies to investigate receptor binding affinity and structure-activity relationships (SAR) for CNS targets.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Chemical Synthesis: Employed in organic synthesis for the construction of complex heterocyclic compounds with potential biological activity.
• Biochemical Research: Utilized in studies exploring neurotransmitter pathways and the modulation of specific neural receptors.

Basic Information

Product Name	10,11-Dihydro-N,n-Dimethyl-2-[(4-Methyl-1-Piperazinyl)Methyl]-5H-Dibenz[B,F]Azepine-5-Propan-1-Amine
CAS No.	64097-65-0
Molecular Formula	C25H36N4
Molecular Weight	392.58 g/mol
Synonyms	10,11-Dihydro-N,N-dimethyl-2-[(4-methyl-1-piperazinyl)methyl]-5H-dibenzo[b,f]azepine-5-propan-1-amine; 2-[(4-Methylpiperazin-1-yl)methyl]-10,11-dihydro-N,N-dimethyl-5H-dibenzo[b,f]azepine-5-propan-1-amine; Desmethylclozapine; Norclozapine; Clozapine N-Desmethyl Metabolite; 64097-65-0; 5H-Dibenz[b,f]azepine-5-propanamine, 10,11-dihydro-N,N-dimethyl-2-[(4-methyl-1-piperazinyl)methyl]-
EINECS	Contact for details

Quality Control

Our 10,11-Dihydro-N,n-Dimethyl-2-[(4-Methyl-1-Piperazinyl)Methyl]-5H-Dibenz[B,F]Azepine-5-Propan-1-Amine is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing purity, impurities, and other critical parameters are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.