Description

10,11-Dihydro-N,n-Dimethyl-2-(1-Piperidinylmethyl)-5H-Dibenz[B,F]Azepine-5-Ethanamine is a high-purity pharmaceutical intermediate and research chemical with a complex tricyclic dibenzazepine structure. This compound is valued for its role as a key synthetic precursor in the development of active pharmaceutical ingredients (APIs) and for advanced pharmacological research. It is primarily required by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in medicinal chemistry and neuropharmacology studies.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of complex drug molecules, particularly those targeting the central nervous system.
• Medicinal Chemistry Research: Used as a core scaffold or precursor for the design and development of new chemical entities in drug discovery programs.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Research: Employed in in-vitro studies to investigate biological activity and structure-activity relationships (SAR).
• Fine Chemical Synthesis: Utilized in multi-step organic syntheses to introduce the dibenzazepine moiety into more complex molecular architectures.

Basic Information

Product Name	10,11-Dihydro-N,n-Dimethyl-2-(1-Piperidinylmethyl)-5H-Dibenz[B,F]Azepine-5-Ethanamine
CAS No.	64097-62-7
Molecular Formula	C24H31N3
Molecular Weight	361.53 g/mol
Synonyms	10,11-Dihydro-N,N-dimethyl-2-(1-piperidinylmethyl)-5H-dibenzo[b,f]azepine-5-ethanamine; 2-[(1-Piperidinyl)methyl]-10,11-dihydro-N,N-dimethyl-5H-dibenzo[b,f]azepine-5-ethanamine; Dibenzo[b,f]azepine-5-ethanamine, 10,11-dihydro-N,N-dimethyl-2-(1-piperidinylmethyl)-; Lofepramine Impurity; Lofepramine Related Compound; Lofepramine Intermediate; GAM 2201; Tofenacin Derivative
EINECS	Contact for details

Quality Control

Our 10,11-Dihydro-N,n-Dimethyl-2-(1-Piperidinylmethyl)-5H-Dibenz[B,F]Azepine-5-Ethanamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research and synthesis. Certificates of Analysis (COA) documenting purity, related substances, and other critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.