Description

10,11-Dihydro-2-(1-Piperidinylmethyl)-5H-Dibenz[B,F]Azepine is a high-purity, specialized organic compound with the CAS registry number 64097-56-9. This molecule is a key advanced intermediate of significant interest in pharmaceutical research and development, particularly for its structural framework found in bioactive molecules. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and fine chemical industries. Its well-defined structure makes it a critical building block for synthesizing novel therapeutic agents and for use in method development and scale-up studies.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the discovery of new drug candidates.
• Process Chemistry: Employed in route scouting, optimization, and scale-up activities for the production of complex organic molecules.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Biochemical Research: Utilized in studies investigating molecular interactions and as a ligand or probe in biochemical assays.

Basic Information

Product Name	10,11-Dihydro-2-(1-Piperidinylmethyl)-5H-Dibenz[B,F]Azepine
CAS No.	64097-56-9
Molecular Formula	C21H24N2
Molecular Weight	304.43 g/mol
Synonyms	2-[(Piperidin-1-yl)methyl]-10,11-dihydro-5H-dibenzo[b,f]azepine; 10,11-Dihydro-2-(piperidin-1-ylmethyl)-5H-dibenzo[b,f]azepine; Dibenzo[b,f]azepine, 10,11-dihydro-2-(1-piperidinylmethyl)-; Lortalamine Impurity; Lortalamine Related Compound A
EINECS	Contact for details

Quality Control

Our 10,11-Dihydro-2-(1-Piperidinylmethyl)-5H-Dibenz[B,F]Azepine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.