Description

n-Methylcolchiceinamide is a synthetic derivative of the natural alkaloid colchicine, designed for advanced research and pharmaceutical development. This compound is valued for its potential as a key intermediate or active pharmaceutical ingredient (API) in the investigation of novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in oncology, anti-inflammatory, and anti-gout drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel colchicine analogs for drug discovery.
• Biochemical Research: Used as a reference standard or tool compound in studies of tubulin polymerization inhibition and cytoskeleton dynamics.
• Oncology Research: Investigated for its potential anti-mitotic and anti-proliferative effects in various cancer cell line studies.
• Inflammation & Gout Studies: Explored for mechanisms related to its parent compound's activity in modulating inflammatory pathways.
• Academic Research: Employed in university and institutional labs for fundamental pharmacological and chemical research.

Basic Information

Product Name	n-Methylcolchiceinamide
CAS No.	63917-71-5
Molecular Formula	C22H25NO6
Molecular Weight	399.44 g/mol
Synonyms	N-Methylcolchiceinamide; N-Methylcolchiceinamide; N-Methylcolchiceinamide; Colchiceinamide, N-methyl-; N-Methylcolchiceinamide; N-Methylcolchiceinamide; N-Methylcolchiceinamide; N-Methylcolchiceinamide
EINECS	Contact for details

Quality Control

Our n-Methylcolchiceinamide is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.