Description

Urat1 Inhibitor 1 CAS NO 2268720-62-1 is a potent and selective small molecule inhibitor designed to target the Urat1 transporter. This compound is of significant value for research into uric acid metabolism and related disorders. It is primarily needed by pharmaceutical R&D teams and academic researchers focused on developing novel therapeutics for conditions like gout and hyperuricemia.

Application

• Pharmacological Research: A key tool compound for in vitro and in vivo studies of Urat1 (URAT1/SLC22A12) transporter function and inhibition.
• Drug Discovery Programs: Serves as a lead compound or reference standard in the development of new uricosuric agents for treating hyperuricemia and gout.
• Mechanistic Studies: Used to investigate renal urate reabsorption pathways and validate Urat1 as a therapeutic target.
• Biochemical Assay Development: Employed as a control inhibitor in high-throughput screening (HTS) assays to identify new Urat1 modulators.
• Preclinical Evaluation: Supports pharmacokinetic (PK) and pharmacodynamic (PD) studies in animal models of metabolic disease.

Basic Information

Product Name	Urat1 Inhibitor 1
CAS No.	2268720-62-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	URAT1 Inhibitor 1; SLC22A12 Inhibitor; Uric Acid Transporter 1 Inhibitor; Lesinurad analog; RDEA3170 analog; Hyperuricemia inhibitor; Uricosuric agent candidate; Research compound 2268720-62-1
EINECS	Contact for details

Quality Control

Our Urat1 Inhibitor 1 is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. All materials are characterized using advanced analytical techniques, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under inert atmosphere. The product is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.