Description

Febuxostat is a potent, non-purine selective inhibitor of the enzyme xanthine oxidase, which plays a critical role in uric acid production. This mechanism of action makes it a valuable active pharmaceutical ingredient (API) for the treatment of chronic conditions like hyperuricemia and gout. It is primarily utilized by pharmaceutical manufacturers in the research, development, and commercial production of prescription medications. Our supply of Febuxostat CAS NO 1312815-36-3 ensures high purity and reliable consistency for demanding pharmaceutical applications.

Application

• Pharmaceutical API: Primary use as the active ingredient in prescription drugs for managing hyperuricemia in patients with gout.
• Finished Dosage Formulation: Incorporated into tablets and other solid oral dosage forms for commercial drug products.
• Research & Development: Serves as a key reference standard and building block in metabolic disorder research and new drug discovery programs.
• Generic Drug Manufacturing: Essential for companies producing bioequivalent generic versions of branded febuxostat medications.
• Clinical Trial Material: Supplied as GMP-grade material for use in Phase I-III clinical studies.
• Biochemical Research: Used in in vitro studies to investigate xanthine oxidase inhibition and purine metabolism pathways.

Basic Information

Product Name	Febuxostat
CAS No.	1312815-36-3
Molecular Formula	C16H16N2O3S
Molecular Weight	316.38 g/mol
Synonyms	2-[(3-Cyano-4-isobutoxyphenyl)methyl]-4-methyl-1,3-thiazole-5-carboxylic acid; TMX-67; TEI-6720; Uloric (brand name); Adenuric (brand name); Feburic; Febuxostat anhydrous; Non-purine xanthine oxidase inhibitor.
EINECS	Contact for details

Quality Control

Our Febuxostat is manufactured and tested under a strict quality management system. We offer material compliant with current Good Manufacturing Practice (GMP) guidelines for active pharmaceutical ingredients (APIs). Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, ensuring it meets the stringent requirements for pharmaceutical use. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The material is light-sensitive (store away from light). Keep the container tightly sealed in a dry environment to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity: ≤ 0.10% Total impurities: ≤ 0.5%
Heavy Metals	≤ 20 ppm
Solvent Residues (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.