Description

Allopurinol is a xanthine oxidase inhibitor, a critical pharmaceutical intermediate and active pharmaceutical ingredient (API) used to manage uric acid levels. Its primary commercial value lies in its role as the key component for manufacturing gout medications and treatments for hyperuricemia associated with chemotherapy. This compound is essential for pharmaceutical manufacturers, research institutions, and fine chemical suppliers serving the global healthcare sector. Allopurinol CAS NO 291279-53-3 represents a high-purity material vital for ensuring the efficacy and safety of final drug formulations.

Application

• Pharmaceutical API: Primary use as the active ingredient in prescription medications for chronic gout and kidney stones.
• Hyperuricemia Treatment: Formulation into drugs that lower serum urate levels in conditions like tumor lysis syndrome.
• Research & Development: Used in biochemical research to study xanthine oxidase inhibition pathways and metabolic disorders.
• Veterinary Medicine: Application in veterinary pharmaceuticals for treating gout in birds and reptiles.
• Fine Chemical Synthesis: Serves as a key building block or reference standard in the synthesis of related purine analogs.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for generic and branded drug production.

Basic Information

Product Name	Allopurinol
CAS No.	291279-53-3
Molecular Formula	C5H4N4O
Molecular Weight	136.11 g/mol
Synonyms	1H-Pyrazolo[3,4-d]pyrimidin-4-ol; 4-Hydroxypyrazolo[3,4-d]pyrimidine; Zyloprim; Milurit; Allopur; HPP; NSC-1390; BW 56-158
EINECS	Contact for details

Quality Control

Our Allopurinol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. We provide full traceability and support compliance with relevant pharmacopoeial standards (such as USP/EP) and regulatory frameworks including ICH Q7 and GMP guidelines. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.