Description

Verinurad is a potent and selective inhibitor of the uric acid transporter URAT1, playing a critical role in the management of hyperuricemia and gout. This high-purity active pharmaceutical ingredient (API) is essential for the research and development of novel therapeutics targeting renal urate excretion. It is primarily utilized by pharmaceutical companies and research institutions engaged in metabolic disorder drug discovery and formulation.

Application

• Pharmaceutical API: Core active ingredient in the development and manufacturing of prescription medications for the treatment of hyperuricemia and gout.
• Preclinical & Clinical Research: Critical compound for in vitro and in vivo studies to investigate urate-lowering mechanisms, pharmacokinetics, and efficacy.
• Combination Therapy Development: Used in research for fixed-dose combination drugs, often paired with xanthine oxidase inhibitors for enhanced therapeutic effect.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.
• Biochemical Research: Tool compound for studying the function and inhibition of the URAT1 transporter in renal physiology and pathophysiology.

Basic Information

Product Name	Verinurad
CAS No.	1352792-74-5
Molecular Formula	C17H14F3N3O3S
Molecular Weight	397.37 g/mol
Synonyms	RDEA3170; 2-[(3-Cyano-4-isobutoxyphenyl)amino]-4-(trifluoromethyl)pyrimidine-5-carboxamide; URAT1 Inhibitor RDEA3170; 5-Pyrimidinecarboxamide, 2-[(3-cyano-4-isobutoxyphenyl)amino]-4-(trifluoromethyl)-; RDEA-3170
EINECS	Contact for details

Quality Control

Our Verinurad is manufactured under strict quality management systems to meet the exacting standards required for pharmaceutical research and development. Every batch is subjected to comprehensive analytical testing including HPLC for purity and identity confirmation. A detailed Certificate of Analysis (COA) is provided, ensuring traceability and compliance with relevant guidelines for advanced intermediates and APIs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert conditions or in a desiccator to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.