Description

(S)-Sulfinpyrazone CAS NO 159000-48-3 is the single enantiomer form of the established uricosuric agent sulfinpyrazone, offering a high-purity standard for advanced pharmaceutical research and development. This compound is critical for studies focusing on stereoselective pharmacology, particularly in the modulation of renal tubular transport and platelet function. It is primarily utilized by pharmaceutical companies and research institutions engaged in developing novel therapeutics for gout, cardiovascular diseases, and as a reference standard for analytical method development.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a selective probe to study the stereospecific mechanisms of urate anion exchange and organic anion transporters (OATs) in renal physiology.
• Reference Standard: Employed as a high-purity certified reference material (CRM) for quality control and analytical method validation in pharmaceutical laboratories.
• Metabolite Studies: Utilized in the investigation of the metabolic pathways and pharmacokinetics of sulfinpyrazone enantiomers.
• Platelet Aggregation Research: Applied in cardiovascular research to explore the stereochemical aspects of antiplatelet activity.

Basic Information

Product Name	(S)-Sulfinpyrazone
CAS No.	159000-48-3
Molecular Formula	C23H20N2O3S
Molecular Weight	404.48 g/mol
Synonyms	(S)-1,2-Diphenyl-4-[2-(phenylsulfinyl)ethyl]pyrazolidine-3,5-dione; (S)-Sulfinpyrazone; (S)-Anturan; (S)-Anturane; (S)-Sulfinpyrazone enantiomer; (S)-G-28315; (S)-1,2-Diphenyl-3,5-dioxo-4-(2-phenylsulfinylethyl)pyrazolidine; (S)-Enantiomer of Sulfinpyrazone
EINECS	Contact for details

Quality Control

Our (S)-Sulfinpyrazone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity determination by HPLC, to ensure it meets the stringent requirements for pharmaceutical research. A detailed Certificate of Analysis (COA) providing results for identity, purity, and enantiomeric excess is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.