Description

Allopurinol is a potent xanthine oxidase inhibitor, a critical pharmaceutical intermediate and active pharmaceutical ingredient (API) used to manage uric acid levels. Its primary commercial value lies in its role as the key component in medications for treating chronic conditions like gout and hyperuricemia, ensuring consistent therapeutic efficacy. This high-purity compound is essential for manufacturers in the global pharmaceutical, biotechnology, and fine chemical synthesis sectors who require reliable, specification-grade raw materials for formulation and research.

Application

• Pharmaceutical API: Primary use as the active ingredient in anti-gout and hyperuricemia medications (e.g., Zyloprim, Lopurin).
• Fine Chemical Synthesis: Serves as a key intermediate in the synthesis of more complex purine analogs and related therapeutic agents.
• Biochemical Research: Used as a standard and inhibitor in enzymatic studies, particularly for xanthine oxidase activity assays.
• Veterinary Medicine: Formulated for the treatment of urate urolithiasis and hyperuricemia in certain animal species.
• Reference Standard: Employed as a high-purity certified reference material (CRM) for quality control and analytical method development in laboratories.

Basic Information

Product Name	Allopurinol
CAS No.	315-30-0
Molecular Formula	C5H4N4O
Molecular Weight	136.11 g/mol
Synonyms	1H-Pyrazolo[3,4-d]pyrimidin-4-ol; 4-Hydroxypyrazolo[3,4-d]pyrimidine; Zyloprim; Lopurin; HPP; Allopur; NSC-1390; BW 56-158; NSC 1390
EINECS	206-250-9

Quality Control

Our Allopurinol is manufactured under strict quality management systems, with grades available to meet USP, EP, and BP pharmacopeial standards. Each batch undergoes comprehensive analytical testing including identity, purity, and impurity profile verification to ensure it meets the stringent requirements for pharmaceutical use. A Certificate of Analysis (COA) documenting all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC)	98.0% - 102.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Microbial Limits	Meets EP/USP requirements

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.