Description

Dotinurad is a selective urate reabsorption inhibitor (SURI) used as an active pharmaceutical ingredient (API). This compound is significant for its role in the development of novel therapeutics for the management of hyperuricemia and gout. It is primarily needed by pharmaceutical manufacturers and research institutions engaged in the formulation of new drugs and clinical studies.

Application

• Active Pharmaceutical Ingredient (API) in the formulation of prescription medications for hyperuricemia.
• Key intermediate in advanced pharmaceutical research and development for gout treatment.
• Reference standard for analytical method development and quality control in pharmaceutical laboratories.
• Biochemical research tool for studying urate transporter 1 (URAT1) inhibition mechanisms.

Basic Information

Product Name	Dotinurad
CAS No.	1285572-51-1
Molecular Formula	C₁₇H₁₄F₃N₃O₃S
Molecular Weight	397.37 g/mol
Synonyms	Dotinurad; UR-1102; 2-[(3,5-Difluorophenyl)carbamoyl]-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylic acid 1,1-dioxide; UR 1102; UR1102; S-4481; S4481; (2-{[(3,5-Difluorophenyl)carbamoyl]}-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-3-yl)acetic acid 1,1-dioxide
EINECS	Contact for details

Quality Control

Our Dotinurad is manufactured under cGMP conditions and undergoes rigorous quality testing to ensure compliance with ICH Q7 guidelines and other relevant pharmaceutical standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each batch.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single unknown impurity ≤ 0.2%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.