Description

Brofaromine is a selective and reversible inhibitor of monoamine oxidase A (MAO-A), belonging to the class of pharmaceutical intermediates and research biochemicals. This compound is of significant interest for its role in the development of novel antidepressant and anxiolytic therapeutics. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions engaged in neuroscience and psychopharmacology research.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis and research of advanced MAO inhibitor drug candidates.
• Neuroscience Research: Used as a reference standard and active compound in studies investigating monoamine oxidase function and neurotransmitter regulation.
• Preclinical Development: Employed in in vitro and in vivo models to assess efficacy, pharmacokinetics, and safety profiles of potential CNS-active agents.
• Biochemical Assay Development: Serves as a critical control or inhibitor in enzymatic assays targeting MAO-A activity for high-throughput screening.
• Reference Standard: Used for analytical method development, validation, and quality control (HPLC, LC-MS) in pharmaceutical analysis.

Basic Information

Product Name	Brofaromine
CAS No.	63638-91-5
Molecular Formula	C₁₇H₁₉BrN₂O₂
Molecular Weight	363.25 g/mol
Synonyms	4-Bromo-N-(2-morpholinoethyl)benzamide; CGP 11,305 A; Ro 11-1163; Brofaronin; (4-Bromophenyl)-[2-(4-morpholinyl)ethyl]carboxamide; 4-Bromo-N-[2-(morpholin-4-yl)ethyl]benzamide
EINECS	Contact for details

Quality Control

Our Brofaromine is manufactured under a quality management system and undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing specifications such as assay, related substances, and residual solvents. Our quality standards are designed to meet the stringent requirements of pharmaceutical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.