Description

8-Azoniabicyclo[3.2.1]Octane, 8-(2-Fluoroethyl)-3-[(2-Hydroxy-2,2-Diphenylacetyl)Oxy]-8-Methyl-, Bromide (1:1), (3-Endo,8-Anti)- is a high-purity, complex organic salt with a quaternary ammonium structure, primarily utilized as a key pharmaceutical intermediate in advanced synthesis. Its precise stereochemistry and functional groups make it a critical building block for researchers and manufacturers developing active pharmaceutical ingredients (APIs). This compound is essential for organizations in the pharmaceutical, agrochemical, and advanced material research sectors requiring reliable, high-quality intermediates for complex organic transformations.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of complex drug molecules, particularly those targeting the nervous system.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core scaffold for research and development of new therapeutic agents.
• Chiral Building Block: Used in asymmetric synthesis due to its defined (3-Endo,8-Anti) stereochemistry to create enantiomerically pure compounds.
• Agrochemical Research: Potential intermediate in the development of advanced pesticides or herbicides requiring specific biological activity.
• Neurological Research Compounds: Applied in the development of ligands and probes for neurological targets, given its structural similarity to tropane alkaloids.
• Chemical Biology & Proteomics: Can be utilized as a specialty reagent or a tagged molecule in biochemical studies and probe development.

Basic Information

Product Name	8-Azoniabicyclo[3.2.1]Octane, 8-(2-Fluoroethyl)-3-[(2-Hydroxy-2,2-Diphenylacetyl)Oxy]-8-Methyl-, Bromide (1:1), (3-Endo,8-Anti)-
CAS No.	63516-10-9
Molecular Formula	C24H29BrFNO3
Molecular Weight	478.40 g/mol
Synonyms	8-(2-Fluoroethyl)-3-[(hydroxydiphenylacetyl)oxy]-8-methyl-8-azoniabicyclo[3.2.1]octane bromide; 3-Tropanyl 2-fluoroethyl(8-methyl-8-azabicyclo[3.2.1]oct-3-yl) diphenylglycolate bromide; Fluorotropium bromide; (3-endo,8-anti)-8-(2-Fluoroethyl)-3-[(2-hydroxy-2,2-diphenylacetoxy]-8-methyl-8-azoniabicyclo[3.2.1]octane bromide; 8-Methyl-8-(2-fluoroethyl)-3α-[(2-hydroxy-2,2-diphenylacetoxy]tropanium bromide; Tropane-3α-ol, 8-(2-fluoroethyl)-8-methyl-, ester with benzilic acid, bromide; Benzilic acid 8-(2-fluoroethyl)-8-methyl-3α-tropanyl ester bromide
EINECS	Contact for details

Quality Control

Our 8-Azoniabicyclo[3.2.1]Octane derivative is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing identity, purity, and impurity profiles. Our quality protocols are designed to meet the stringent requirements of cGMP (current Good Manufacturing Practice) for advanced intermediates, ensuring traceability and reliability for our global clientele.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.